Title:
がん特異的酵素活性を利用したプロドラッグ型抗がん剤
Document Type and Number:
Japanese Patent JPWO2019172210
Kind Code:
A1
Abstract:
【解決課題】プロドラッグ型抗がん剤として有望な新規化合物を提供すること。【解決手段】以下の一般式（Ｉ）で表される化合物又はその塩。
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Inventors:
Yasuteru Urano
Kamiya Mako
Kento Hayashi
Kamiya Mako
Kento Hayashi
Application Number:
JP2020505030A
Publication Date:
February 25, 2021
Filing Date:
March 04, 2019
Export Citation:
Assignee:
National University Corporation Tokyo University
International Classes:
C07C237/04; A61K31/198; A61K31/205; A61K31/40; A61K31/7034; A61P35/00; A61P43/00; C07D207/16; C07H15/203
Domestic Patent References:
| JP2017502068A | 2017-01-19 |
Foreign References:
| WO2015178265A1 | 2015-11-26 | |||
| CN106831904A | 2017-06-13 | |||
| CN102603695A | 2012-07-25 | |||
| US20060142202A1 | 2006-06-29 | |||
| WO2008079924A1 | 2008-07-03 |
Other References:
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JOURNAL OF MEDICINAL CHEMISTRY, vol. 24(5), JPN6023005311, 1981, pages 479 - 480, ISSN: 0004988753
JOURNAL OF ORGANIC CHEMISTRY, vol. 80(16), JPN6023005306, 2015, pages 8458 - 8463, ISSN: 0004988748
JOURNAL OF THE CHINESE CHEMICAL SOCIETY (TAIPEI, TAIWAN), vol. 53(2), JPN6023005307, 2006, pages 479 - 488, ISSN: 0004988749
BIOORGANIC CHEMISTRY, vol. 18(3), JPN6023005308, 1990, pages 330 - 344, ISSN: 0004988750
BIOCONJUGATE CHEMISTRY, vol. 27(3), JPN6023005309, 2016, pages 660 - 666, ISSN: 0004988751
Attorney, Agent or Firm:
Makoto Ono
Kenkyo Kanayama
Mitsuaki Tsubokura
Kazuki Shigemori
Kenji Ando
Hidehiko Ichikawa
Yoshie Sakurada
Yousuke Kawasaki
Takuya Gomibuchi
Yoichi Iino
Yusuke Ichikawa
Masahiro Moriyama
Takashi Kono
Yoshikazu Iwase
Yasufumi Shiroyama
Kenkyo Kanayama
Mitsuaki Tsubokura
Kazuki Shigemori
Kenji Ando
Hidehiko Ichikawa
Yoshie Sakurada
Yousuke Kawasaki
Takuya Gomibuchi
Yoichi Iino
Yusuke Ichikawa
Masahiro Moriyama
Takashi Kono
Yoshikazu Iwase
Yasufumi Shiroyama