Title:
DETECTION OF AMPLIFIED DNA/RNA BY FLUORESCENCE POLARIZATION
Document Type and Number:
WIPO Patent Application WO/1991/006680
Kind Code:
A1
Abstract:
A homogenous method for detecting amplified RNA or DNA target sequences utilizes signal-labelled DNA or RNA probes which show detectably increased fluorescence polarization when hybridized to target sequences. A convenient one-step analytical procedure requiring no nucleic acid extraction or signal separation step is thereby provided.
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Inventors:
Wang, Chao-huei Jeffrey (Gurnee, IL, US)
Ammons, Harryl (#3 Waukegan, IL, US)
Jolley, Michael E. (Round Lake, IL, US)
Ammons, Harryl (#3 Waukegan, IL, US)
Jolley, Michael E. (Round Lake, IL, US)
Application Number:
PCT/US1990/006299
Publication Date:
May 16, 1991
Filing Date:
October 30, 1990
Export Citation:
Assignee:
BAXTER INTERNATIONAL INC. (Deerfield, Il, US)
International Classes:
(IPC1-7): C12Q1/68; C07H15/12; C12N15/00
Attorney, Agent or Firm:
Barta, Kent S. (Deerfield, IL, US)
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