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Title:
〔1,2〕-ジチオラン部分を含有する抗酸化剤重合体およびその使用
Document Type and Number:
Japanese Patent JP2010520333
Kind Code:
A
Abstract:
The present invention describes polymers containing 1,2-dithiolanes capable of acting as scavengers of free radicals, metals and reactive oxygen species. Also described are methods of synthesizing the antioxidant 1,2-dithiolane derivatives and polymerization thereof to produce biodegradable antioxidant polymers. The antioxidant polymers of the present invention may be used to treat diseases or conditions caused by oxidative stress and other free radical mediated conditions. The antioxidant polymers may also be used for the preparation of antioxidant particulate delivery devices of therapeutic agents.

Inventors:
You, John S.
Lee, Bonsop
Application Number:
JP2009551871A
Publication Date:
June 10, 2010
Filing Date:
February 29, 2008
Export Citation:
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Assignee:
Cedars-Sinai Medical Center
International Classes:
C08G65/34; C07D339/04; C08G73/00
Domestic Patent References:
JP2000086620A2000-03-28
JPH08106158A1996-04-23
JP2002323497A2002-11-08
JP2002506029A2002-02-26
JP2002537253A2002-11-05
JP2000511517A2000-09-05
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita