Title:
(+) -1 and 4-dihydro7- [(3S, 4S) -3 - methoxy -- 4- (methylamino) -1-pyrrolidinyl] -4 - oxo -- a manufacturing method of 1- (2-thiazolyl) -1 and 8- Nauchi lysine 3-carboxylic acid
Document Type and Number:
Japanese Patent JP6129471
Kind Code:
B2
Abstract:
Described herein is a composition having at least 99.95% (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid and less than 0.05% (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-amino-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid based on total weight of the composition, and uses thereof.
Inventors:
Anant Hasdhakar
Tamil Alassan Subra Mani
Mohamed Sheikh Mohamed Mjeev Rahman
Lamar Subhiv
Tamil Alassan Subra Mani
Mohamed Sheikh Mohamed Mjeev Rahman
Lamar Subhiv
Application Number:
JP2011544574A
Publication Date:
May 17, 2017
Filing Date:
December 29, 2009
Export Citation:
Assignee:
MILLENNIUM PHARMACEUTICALS, INC.
International Classes:
C07D471/04; A61K31/4375; A61P35/00; A61P35/02; C07D207/14
Domestic Patent References:
| JP11349565A | ||||
| JP7188124A | ||||
| JP2218664A | ||||
| JP2015180677A |
Other References:
Tetrahedron:Asymmetry,(2001),Vol.12,No.21,pp.2989-2997
日本化学会編,「実験化学講座18 有機化合物の反応II(上)」,丸善株式会社,昭和32年11月25日発行,第531-546頁
日本化学会編,「実験化学講座18 有機化合物の反応II(上)」,丸善株式会社,昭和32年11月25日発行,第531-546頁
Attorney, Agent or Firm:
Harakenzo world patent & trademark