DPP-IV阻害剤としての1-アミノメチル-1-フェニル-シクロヘキサン誘導体

Japanese Patent JP2010513357

A

Compounds of the formula (I) are provided: wherein V, W, X, Y, Z, R3, R4, R5, R6, R7 and m are as defined in the specification; and pharmaceutically acceptable salts and prodrugs thereof. The compounds may be useful in the treatment or prevention of various diseases and conditions in which dipeptidylpeptidase-IV (DPP-IV) is implicated.

Daniel Caspar Beshulin
Richard Cedrani
Stephanie flor
Kenji Namoto
Phanton Sirocan
Francois Jessier
Garry Fenton
Mandy Christine Beswick
David Edward Clark
Bourdan Waskowitz

JP2009541899A

April 30, 2010

December 20, 2007

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Novartis Age

C07C311/08; A61K31/137; A61K31/351; A61K31/357; A61K31/36; A61K31/381; A61K31/4015; A61K31/4035; A61K31/415; A61K31/4192; A61K31/421; A61K31/433; A61K31/437; A61K31/4418; A61K31/445; A61K31/4545; A61K31/472; A61K31/495; A61K31/4965; A61K31/4985; A61K31/519; A61K31/5377; A61K31/55; A61K31/551; A61K45/00; A61P1/00; A61P1/02; A61P3/04; A61P3/06; A61P3/10; A61P9/04; A61P9/10; A61P9/12; A61P13/08; A61P13/12; A61P19/02; A61P19/10; A61P25/20; A61P25/22; A61P25/28; A61P27/02; A61P29/00; A61P35/04; A61P43/00; C07C311/20; C07C317/32; C07D207/408; C07D209/44; C07D211/26; C07D213/85; C07D217/06; C07D223/04; C07D231/12; C07D239/42; C07D241/08; C07D243/08; C07D249/18; C07D263/22; C07D265/10; C07D285/06; C07D295/12; C07D307/68; C07D309/14; C07D317/58; C07D333/20; C07D401/04; C07D403/10; C07D409/04; C07D413/04; C07D471/04; C07D487/04; C07D498/04; C07D513/04

JP2002528490A	2002-09-03
JP2000510833A	2000-08-22
JPS5010309B1	1975-04-19

WO2005105096A2	2005-11-10
WO2005108384A1	2005-11-17
WO2007000376A1	2007-01-04

Mitsuo Tanaka
Takuji Yamada
Mitsutaka Iwasaki
Aoyama Aoi
Masayuki Nakagawa

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