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Title:
1-メチル-3-ケト-Δ▲上1,4▼-ステロイドの製法
Document Type and Number:
Japanese Patent JP3770904
Kind Code:
B2
Abstract:
PCT No. PCT/EP93/01606 Sec. 371 Date Apr. 18, 1995 Sec. 102(e) Date Apr. 18, 1995 PCT Filed Jun. 22, 1993 PCT Pub. No. WO94/04553 PCT Pub. Date Mar. 3, 1994.A process for the production of 1-methyl-3-keto- DELTA 1,4 steroids of general formula I (I) in which St symbolizes the radical of asteroid molecule, where a 3-keto- DELTA 1,4 steroid of general formula II (II) in which St has the above-mentioned meaning, is reacted in an inert solvent in the presence of a nickel salt soluble therein with an organometallic compound of formula III, IV or V CH3ZnX, (III) d Z2 are as defined in the specification.

Inventors:
Westermann, Jurgen
Nikish, Claus
Pralle, Anette
Application Number:
JP50581194A
Publication Date:
April 26, 2006
Filing Date:
June 22, 1993
Export Citation:
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Assignee:
Schering Aktiengesellschaft
International Classes:
C07J75/00; C07J1/00; C07J21/00
Domestic Patent References:
JP63287796A
Other References:
BAGNELL, L., et al., Austr. J. Chem., 28(4), pp.801-815 (1975)
ASHBY, E.C., et al., J. Org. Chem., 39(22), pp.3297-3299 (1974)
Attorney, Agent or Firm:
Toshio Yano
Toshiomi Yamazaki
Takuya Kuno
Reinhard Einsel