Title:
腫瘍壊死因子産生の阻害剤として1-オキサ-ジベンゾアズレン及びその製造用中間体
Document Type and Number:
Japanese Patent JP2005532327
Kind Code:
A
Abstract:
The present invention relates to 1-oxa-dibenzoazulene derivatives, to their pharmacologically acceptable salts and solvates, to processes and intermediates for the preparation thereof as well as to their antiinflammatory effects, especially to the inhibition of tumour necrosis factor-alpha (TNF-alpha) production and the inhibition of interleukin-1 (IL-1) production as well as to their analgetic action.
Inventors:
Mersep, Muraden
Methic, Milan
Pesic, dyana
Methic, Milan
Pesic, dyana
Application Number:
JP2004505381A
Publication Date:
October 27, 2005
Filing Date:
May 20, 2003
Export Citation:
Assignee:
PRIVA-Istra Tsv Atsky Institute Day Oh Oh
International Classes:
A61K31/335; A61K31/34; A61K31/343; A61K31/38; A61K31/55; A61P1/00; A61P1/04; A61P11/06; A61P17/04; A61P17/06; A61P19/00; A61P19/02; A61P27/02; A61P29/00; A61P35/00; A61P43/00; C07D307/00; C07D313/00; C07D403/04; C07D493/02; C07D493/04; C07D495/02; C07D497/02; (IPC1-7): C07D493/04; A61K31/335; A61P1/00; A61P1/04; A61P11/06; A61P17/04; A61P17/06; A61P19/00; A61P19/02; A61P27/02; A61P29/00; A61P43/00
Attorney, Agent or Firm:
Takao Hamano
Morita Tetsuji
Teruichi Hirai
Morita Tetsuji
Teruichi Hirai