Title:
11 ALPHA-AMINO-3 BETA-HYDROXYANDROSTANE COMPOUND
Document Type and Number:
Japanese Patent JPS57158800
Kind Code:
A
Abstract:
Compounds of the formula (I) wherein R1 is a C1-8 alkyl group or a C3-7 cycloalkyl group, and R2 is a C1-6 alkyl group or a C3-6 cycloalkyl group and the D-homo analogues thereof having the group -CO2R2 (wherein R2 is as defined above) at the 17 alpha beta -position, and acid addition salts thereof have activity as antidysthythmic agents and may be applicable for the treatment of dysrthymias in humans or animals. The compounds may be provided in the form of compositions in admixture with pharmaceutical carriers and excipients and may be prepared by a variety of processes known for producing steroids of this type. The invention also provides intermediates for the preparation of the compounds of formula (I) wherein R2 and/or R1 are replaced with hydrogen atoms, and processes for the preparation of such intermediates.
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Inventors:
GOODON HANREI FUIRITSUPUSU
DEIBITSUDO SEDORITSUKU HANBAA
JIYOOJI BURANCHI YUUAN
BARII ANTONII KUUMAA
DEIBITSUDO SEDORITSUKU HANBAA
JIYOOJI BURANCHI YUUAN
BARII ANTONII KUUMAA
Application Number:
JP3067482A
Publication Date:
September 30, 1982
Filing Date:
March 01, 1982
Export Citation:
Assignee:
GLAXO GROUP LTD
International Classes:
A61K31/56; A61P9/06; A61P9/10; C07J41/00; C07J63/00; (IPC1-7): A61K31/56; C07J41/00