Title:
11OR 22ADAMANTYLMETHYL HYDRAZINES OR THEIR ACIDDADDED SALT
Document Type and Number:
Japanese Patent JPS5481254
Kind Code:
A
Abstract:
The invention provides novel 1- or 2-adamantylmethyl hydrazines of the general formula A A In this formula Ad is 1- or 2-adamantyl, R1 and R2 are the same or different and are each hydrogen or a lower unsubstituted or substituted alkyl group of 1-4 carbon atoms; R3 and R4 are the same or different and are each hydrogen, an unsubstituted or substituted radical being a lower alkyl group of 1-4 carbon atoms a lower alkanoic acid radical of 2-4 carbon atoms or a lower alkyl ester thereof, adamantyl, aryl, aralkyl in which the alkyl moiety has 1-4 carbon atoms or an unsubstituted or substituted heterocyclic radical of aromatic character; or R3 and R4 together with the nitrogen atom to which they are attached form a cyclic radical or non-aromatic character. The invention further provides pharmaceutically acceptable acid addition salts of the above compounds. Several methods of preparation of the new compounds are described. The novel compounds according to the invention possess valuable antifungal (human and plant), antiviral, antiprotozoal and antimicrobial properties.
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Inventors:
BENNJION BEINERU
JIEFUREI SUTERURINGU
RAURU SUCHI
HAIMU IERIN
JIEFUREI SUTERURINGU
RAURU SUCHI
HAIMU IERIN
Application Number:
JP14492878A
Publication Date:
June 28, 1979
Filing Date:
November 21, 1978
Export Citation:
Assignee:
TEVA PHARMA
International Classes:
A01N33/26; A61K31/185; A61K31/195; A61K31/215; A61P31/04; A61P31/10; A61P31/12; C07C67/00; C07C241/00; A61K31/15; C07C243/14; C07C243/18; C07C243/22; C07D213/77; C07D215/28; C07D215/42; C07D233/80; C07D295/22; C07D295/30; C07D327/06; (IPC1-7): A01N9/20; A01N9/22; A61K31/15; A61K31/185; A61K31/215; C07C109/00; C07C109/04; C07D295/00; C07D327/06