1,2-DIHYDRONAPHTHALENE-1, 3-DICARBOXYLIC ACID DERIVATIVE

Title:

1,2-DIHYDRONAPHTHALENE-1, 3-DICARBOXYLIC ACID DERIVATIVE

Document Type and Number:

Japanese Patent JPH0525082

Kind Code:

A

Abstract:

PURPOSE: To provide the subject novel compound useful as an antiinflammatory agent.

CONSTITUTION: A compound of formula I [Z1 is H, group of formula II; Z2 is H, group of formula III; R1, R2 are H, methyl, but when Z2 is H, R1 is H, and when Z1 is H, R2 id also H), e.g. 1,2-dethdro-7, 8-dihydroxy-1-(3,4- dihydroxyphenyl)-3-[1-carboxy-2-(3,4-dihydroxyphenyl)-naphthalene-1, 3- dicarboxylic acid. The compound of formula I is produced by immersing Mentha haplocalyx BRI Q, in acetone-water mixture, distilling away the acetone from the extraction solution under seduced pressure, and subsequently treating the remaining aqueous solution by column chromatography.

Inventors:

MATANO YUTAKA
WATANO TOMOKAZU
ONO AKIKO
KANITA MICHIHIDE
SAITO YUJI
SUZUKI AKIRA

Application Number:

JP20755591A

Publication Date:

February 02, 1993

Filing Date:

July 23, 1991

Export Citation:

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Assignee:

KANEBO LTD

International Classes:

A61K31/19; A61K31/225; A61P29/00; C07C62/32; C07C69/757; (IPC1-7): A61K31/19; A61K31/225; C07C62/32; C07C69/757

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