アテローム性動脈硬化症および肥満の治療のためのCETP阻害剤としての1,2,4-置換1,2,3,4-テトラヒドロ-および1,2-ジヒドロ-キノリンおよび1,2,3,4-テトラヒドロ-キノキサリン誘導体

Japanese Patent JP2006521344

A

Quinoline and quinoxaline compounds of formula I and III wherein the subtituent are as defined in claims 1 and 15, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans.

JPS60248672	USE OF 5,6,7,8-TETRAHYDROQUINOLINES AND 5,6-DIHYDROPYRIDINESAS LEUKOTRIENE AND LIPXYGENASE INHIBITOR AND THEIR NOVEL 3-SUBSTITUTED COMPOUNDS
JP2007515422	Drugs for the treatment of crystal cavity formation in diabetic retinopathy and macular degeneration
WO/2007/014885	ANTIBACTERIAL QUINOLINE DERIVATIVES

George Chan
Mary Teresa Didiuk
Yari Ilmari Fineman
Ravi Shanker Garigi Patty
Ryan Mikel Kelly
David Austin Peri
Roger Benjamin Rugeri
Bruce Mickle Beckle
Miklee Py Pastry

JP2006506369A

September 21, 2006

March 15, 2004

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Pfizer Products Inc.

C07D215/12; A61K31/4365; A61K31/4375; A61K31/47; A61K31/4709; A61K31/498; A61K31/5377; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P9/00; A61P9/10; A61P9/12; A61P15/10; A61P25/00; A61P25/28; A61P29/00; A61P31/04; A61P39/06; A61P43/00; C07D215/14; C07D215/18; C07D215/20; C07D215/50; C07D241/42; C07D401/04; C07D401/06; C07D401/12; C07D403/06; C07D403/10; C07D405/06; C07D405/12; C07D409/06; C07D409/12; C07D413/06; C07D413/10; C07D413/12; C07D417/06; C07D417/12; C07D417/14; C07D471/04; C07D495/04; A61J7/00; A61J7/04

Chika Takagi
Junji Yuda
Shoji Miwa

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