Title:
1,4-ベンゾジアゼピン-2-オン誘導体
Document Type and Number:
Japanese Patent JP2012517997
Kind Code:
A
Abstract:
The present invention relates to a compound represented by a formula (I): wherein R1 represents a halogen atom or the like; R2 represents a hydrogen atom or the like; R3 and R4 each independently represents lower alkyl; R5 represents phenyl or the like; R6 represents a halogen atom or the like; m is an integer of from 0 to 2; p is an integer of from 1 to 4; and q is an integer of from 1 to 5 as an inhibitor of DGAT1 and its use for the treatment of hyperlipidemia etc.
Inventors:
Masanori Asai
Tadashi Hadada
Seiichi Inamura
Hideki Kurihara
Teruyuki Nishimura
Shimamura Sei
Tadashi Hadada
Seiichi Inamura
Hideki Kurihara
Teruyuki Nishimura
Shimamura Sei
Application Number:
JP2011549841A
Publication Date:
August 09, 2012
Filing Date:
February 12, 2010
Export Citation:
Assignee:
VERTEX PHARMACEUTICALS INCORPORATED
International Classes:
C07D243/14; A61K31/5513; A61P3/04; A61P3/06; A61P3/10; A61P43/00; C12N15/09
Attorney, Agent or Firm:
Yoshikazu Iwase
Makoto Ono
Kenkyo Kanayama
Mitsuaki Tsubokura
Kazuki Shigemori
Kenji Ando
Yasufumi Shiroyama
Makoto Ono
Kenkyo Kanayama
Mitsuaki Tsubokura
Kazuki Shigemori
Kenji Ando
Yasufumi Shiroyama