Title:
１５，１６−メチレン−１７−（１’−プロペニル）−１７−３’−オキシドエストラ−４−エン−３−オン誘導体、その使用及び誘導体含有薬物
Document Type and Number:
Japanese Patent JP5600070
Kind Code:
B2
Abstract:
The invention relates to 15,16-methylene-17-(1'-propenyl)-17-3'-oxidoestra-4-en-3-one derivatives with the general chemical formula I, where the Z, R4, R6a, R6b, R7 and R18 have the meanings stated in claim 1, and solvates, hydrates and salts thereof, including all crystal modifications and all stereoisomers of these compounds. The invention also relates to the use of these derivatives for the production of a drug for oral contraception and for the treatment of pre-, peri- and postmenopausal problems and drugs which contain such derivatives, in particular use in the aforesaid indications. The derivatives according to the invention have a progestational and in preferable cases also an antimineralcorticoid and neutral to slight androgenic activity.
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Inventors:
Krall, Ulrich
クーンケ, Joachim
A ball man, Rolf
Hubner, Jan
A link, スフェン
Frenzel, Thomas
Menges, Frederic
ボルデン, Steffen
The moon, Hans-Petter
プレーレ, カトヤ
クーンケ, Joachim
A ball man, Rolf
Hubner, Jan
A link, スフェン
Frenzel, Thomas
Menges, Frederic
ボルデン, Steffen
The moon, Hans-Petter
プレーレ, カトヤ
Application Number:
JP2010540081A
Publication Date:
October 01, 2014
Filing Date:
December 23, 2008
Export Citation:
Assignee:
Beyer intellectual property gesellschaft mitt ベシュレンクテル ハフツング Bayer Intellectual Property GmbH
International Classes:
C07J53/00; A61K31/565; A61K31/58; A61P5/26; A61P5/34; A61P5/42; A61P15/12; A61P15/18; A61P43/00
Attorney, Agent or Firm:
Aoki 篤
Ishida 敬
Tsumoru Fukumoto
Tetsuji Koga
Yoichi Watanabe
Nakajima 勝
Ryotaro Takei
Ishida 敬
Tsumoru Fukumoto
Tetsuji Koga
Yoichi Watanabe
Nakajima 勝
Ryotaro Takei
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