Title:
17アルファ-カルボネート置換基を有する17ベータ-フルオロメトキシカルボニル-アンドロスタ-4-エン-3-オン化合物
Document Type and Number:
Japanese Patent JP2009515844
Kind Code:
A
Abstract:
The present invention is directed to compounds of formula (I): wherein R1 represents C4-C7 branched chain alkyl, C3-C8 cycloalkyl optionally substituted by one or more groups independently selected from C1-C3 alkyl and methoxy, C4-C6 cycloalkylmethyl wherein the methyl group is optionally substituted by a group selected from methyl or ethyl, or a bicycloalkyl group optionally substituted by one or more methyl groups; R2 represents hydrogen, a methyl group, which may be in either the a or D configuration, or a methylene group; R3 and R4 are the same or a different group and each independently represents hydrogen, halogen or a methyl group; and ![]()
represents a single or a double bond; physiologically acceptable solvates thereof, pharmaceutical compositions thereof, methods of treatment using such compounds, and processes for preparing such compounds.
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Inventors:
Biga dyke, keith
Needham, Deborah
Needham, Deborah
Application Number:
JP2008539361A
Publication Date:
April 16, 2009
Filing Date:
November 13, 2006
Export Citation:
Assignee:
GLAXO GROUP LIMITED
International Classes:
C07J3/00; A61K31/569; A61K45/00; A61P29/00; A61P37/08; C07C68/02; C07C68/06; C07C69/96
Domestic Patent References:
| JPS5745200A | 1982-03-13 |
Attorney, Agent or Firm:
Yusuke Hiraki
Ishii Teiji
Satoshi Fujita
Shinji Endo
Ishii Teiji
Satoshi Fujita
Shinji Endo