Title:
17-HALOGENETHYNYLSTEROID, MANUFACTURE OF SAME AND MANUFACTURE OF PREGNANE DERIVATIVE
Document Type and Number:
Japanese Patent JPS6034990
Kind Code:
A
Abstract:
17-haloethynyl steroids of the partial formula wherein R1 is hydrogen or methyl, R2 is alkyl of 1-4 carbon atoms, acyl of 1-7 carbon atoms, trimethylsilyl, 2-tetrahydropyranyl, or nitrate, X is bromine or iodine, and V is methylene, ethylene, vinylene, ethylidene, vinylidene or cyclopropylene, can be prepared by treating an ethynyl steroid of the partial formula wherein R1, R2, and V are as defined above, in an inert solvent with a brominating agent or an iodinating agent in the presence of a silver salt. Certain new compounds are also provided.
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Inventors:
HERUMUUTO HOOFUMAISUTAA
HENRII RAURENTO
KURAUSU ANEN
RUUDORUFU BUIIHIERUTO
HENRII RAURENTO
KURAUSU ANEN
RUUDORUFU BUIIHIERUTO
Application Number:
JP8211184A
Publication Date:
February 22, 1985
Filing Date:
April 25, 1984
Export Citation:
Assignee:
SCHERING AG
International Classes:
C07J1/00; C07J5/00; C07J7/00; C07J17/00; C07J41/00; C07J51/00; C07J53/00; C07J63/00; (IPC1-7): C07J7/00; C07J53/00; C07J63/00
Domestic Patent References:
JPS52151157A | 1977-12-15 | |||
JP39015829A | ||||
JP41012305A |
Attorney, Agent or Firm:
Toshio Yano