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Title:
177-Lu LABELED PEPTIDE FOR SITE-SPECIFIC uPAR-TARGETING
Document Type and Number:
Japanese Patent JP2019077712
Kind Code:
A
Abstract:
To provide a 177-Lu labeled peptide for site-specific targeting of the urokinase plasminogen activator receptor (uPAR) thereby enabling treatment of a cancer disease associated with high uPAR expression, e.g., treatment of colorectal cancer by administering to a patient an effective amount of the 177-Lu labeled peptide.SOLUTION: The invention provides a 177-Lu labeled uPAR binding peptide conjugate, where the peptide is coupled to 177-Lu by a chelating agent.SELECTED DRAWING: Figure 1

Inventors:
ANDREAS KJAER
MORTEN PERSSON
MICHAEL PLOUG
Application Number:
JP2019005811A
Publication Date:
May 23, 2019
Filing Date:
January 17, 2019
Export Citation:
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Assignee:
RIGSHOSPITALET
International Classes:
C07K7/06; A61K33/24; A61K41/00; A61K47/18; A61K47/64; A61P1/00; A61P13/08; A61P35/00; C07K1/13
Attorney, Agent or Firm:
Makoto Onda
Hironobu Onda
Atsushi Honda