Title:
抗炎症性の、17β-カルボチオアートアンドロスタン誘導体である17α複素環エステル
Document Type and Number:
Japanese Patent JP2005500290
Kind Code:
A
Abstract:
There are provided compounds of formula (I) wherein R1 represents C1-6 alkyl or C1-6 haloalkyl; R2 represents a 4-7 membered non-aromatic ring containing 1-3 heteroatoms selected from O, N and S optionally substituted with one or more methyl, ethyl or halogen groups; R3 represents hydrogen, methyl (which may be in either the alpha or beta configuration) or methylene; R4 and R5 are the same or different and each represents hydrogen or halogen; and (a) represents a single or a double bond; and salts and solvates thereof; processes for preparing them and their use in therapy.
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Inventors:
Biga dyke, keith
Jones, Paul
Jones, Paul
Application Number:
JP2003503645A
Publication Date:
January 06, 2005
Filing Date:
June 11, 2002
Export Citation:
Assignee:
GLAXO GROUP LIMITED
International Classes:
A61K9/12; A61K31/18; A61K31/568; A61K45/00; A61K47/06; A61P5/44; A61P29/00; A61P37/08; A61P43/00; C07J17/00; C07J31/00; C07J33/00; C07J43/00; (IPC1-7): C07J31/00; A61K9/12; A61K31/18; A61K31/568; A61K45/00; A61K47/06; A61P29/00; A61P37/08; A61P43/00
Attorney, Agent or Firm:
Yusuke Hiraki
Ishii Teiji
Satoshi Fujita
Ishii Teiji
Satoshi Fujita