Title:
18-メチル-19-ノル-17-プレグン-4-エン-21,17-カルボラクトンおよびこれを含有する製剤
Document Type and Number:
Japanese Patent JP5043681
Kind Code:
B2
Abstract:
The invention relates to novel 18-methyl-19-nor-17-pregn-4-en-21,17-carbolactones of general formula (I), where Z=O, H2, -NOR or -NNHSO2R, where R=H, a straight- or branched-chain 1-4 or 3-4 C alkyl group, R4=H, halogen, methyl or trifluoromethyl, R6 and/or R7 can be alpha- or beta-positioned and independently=branched- or straight-chain 1-4 or 3-4 alkyl, or R6=H and R7=a- or beta-positioned, straight- or branched-chain 1-4 or 3-4 C alkyl, or R6 and R7=H, or R6 and R7 together=a- or beta-positioned methylene or an additional bond. The novel compounds have gestagenic and antimineralocorticoid activity and are suitable for the production of pharmaceutical preparations, for example, for oral contraception and the treatment of pre-, peri- and post-menopausal pain.
Inventors:
Ballman, Rolf
Bitler, Dieter
Künzer, Hermann
Esperlink, Peter
Moon, Hans-Peter
Fritzheimer, Karl-Heinrich
Furman, Ulrike
Prairie, Katoya
Bolden (Fruehler Kurtz), Steffen
Bitler, Dieter
Künzer, Hermann
Esperlink, Peter
Moon, Hans-Peter
Fritzheimer, Karl-Heinrich
Furman, Ulrike
Prairie, Katoya
Bolden (Fruehler Kurtz), Steffen
Application Number:
JP2007548774A
Publication Date:
October 10, 2012
Filing Date:
December 30, 2005
Export Citation:
Assignee:
Bayer Intellectual Property GmbH
International Classes:
C07J53/00; A61K31/565; A61K31/57; A61K31/585; A61P5/30; A61P15/00; A61P15/12; A61P15/18; (IPC1-7): A01N57/20; A01N25/30
Domestic Patent References:
| JP60161997A |
Foreign References:
| DE3022337A | ||||
| US6177416 | ||||
| US3959322 | ||||
| GB1475790B |
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura