Title:
内寄生生物を制御するための18員ニトロベンジル-およびアミノベンジル-置換シクロヘキサデプシペプチドおよびそれらの製造方法
Document Type and Number:
Japanese Patent JP2007514671
Kind Code:
A
Abstract:
The invention relates to cyclic depsipeptides, especially 18-membered cyclohexadepsipeptides of general formula (I) and the salts thereof, wherein R1 represents nitrobenzyl or R'R''N-benzyl-wherein R' and R'' independently represent hydrogen, optionally substituted C1-C4-alkyl, formyl, C1-C4-alkoxy-C1-C4-alkyl, C1-C4-alkoxycarbonyl, or hydroxy-C1-C2-alkyl-sulfonyl-C1-C2-alkyl, or, together with the nitrogen atom to which they are bound, R' and R'' form an optionally substituted monocyclic or polycyclic, optionally bridged and/or spirocyclic, saturated or unsaturated heterocycle containing between one and three other heteroatoms from the group of nitrogen, oxygen and sulphur, or R' and R'' together form C3-C5-alkylene monocarbonyl or an optionally substituted diacyl radical of a C4-C6-dicarboxylic acid-and R2, R3 and R4 independently represent C1-C4-alkyl. The invention also relates to the optical isomers and racemates of said cyclic depsipeptides, to a method for the production thereof, and to the use of the same for controlling endoparasites.
Inventors:
Peter Yeske
Achim Halder
Achim Halder
Application Number:
JP2006544278A
Publication Date:
June 07, 2007
Filing Date:
December 07, 2004
Export Citation:
Assignee:
Bayer HealthCare AG
International Classes:
C07D273/08; A61K31/395; A61K31/5377; A61K38/15; A61P33/10; C07D273/00; C07K11/02; A61K38/00
Domestic Patent References:
| JPH07252297A | 1995-10-03 | |||
| JP2002502398A | 2002-01-22 | |||
| JPH07223951A | 1995-08-22 | |||
| JPH07206897A | 1995-08-08 | |||
| JPH11506438A | 1999-06-08 |
Foreign References:
| WO1995027498A1 | 1995-10-19 |
Attorney, Agent or Firm:
Aoyama Aoi
Mitsutaka Iwasaki
Yasuo Shibata
Mitsutaka Iwasaki
Yasuo Shibata