Title:
ＰＤＥ１阻害剤としての１Ｈ－ピラゾロ［４，３－ｂ］ピリジン
Document Type and Number:
Japanese Patent JP7096171
Kind Code:
B2
Abstract:
The present invention provides 1H-pyrazolo[4,3-b]pyridin-7-amines of formula (I) as PDE1 inhibitors and their use as a medicament, in particular for the treatment of neurodegenerative disorders and psychiatric disorders.
Inventors:
Kohler, jean
Jules, Kirsten
Marigot, Mauro
Vital, Paul, George, Vieira
Jessing, Mickel
Langard, Molten
Rasmussen, Lars, Keene
Clementson, Carl, Martin, Sebastian
Jules, Kirsten
Marigot, Mauro
Vital, Paul, George, Vieira
Jessing, Mickel
Langard, Molten
Rasmussen, Lars, Keene
Clementson, Carl, Martin, Sebastian
Application Number:
JP2018568885A
Publication Date:
July 05, 2022
Filing Date:
June 30, 2017
Export Citation:
Assignee:
Her Lundbeck Actiezer Scabet
International Classes:
C07D471/04; A61K31/437; A61K31/444; A61K31/497; A61K31/506; A61P25/00; A61P25/14; A61P25/16; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P43/00
Foreign References:
| WO2006044821A1 | ||||
| WO2008111010A1 | ||||
| WO2004056823A1 | ||||
| WO2001018004A2 |
Other References:
YAMAMOTO, S et al.,The effects of a novel phosphodiesterase 7A and -4 dual inhibitor, YM-393059, on T-cell-related cytokine production in vitro and in vivo,European Journal of Pharmacology,2006年,Vol. 541,pp. 106-114
Attorney, Agent or Firm:
Hiroshi Kobayashi
Norio Omori
Taro Ushio
Yasuhito Suzuki
Norio Omori
Taro Ushio
Yasuhito Suzuki