Title:
2-(2,6-DIMETHYL-3,5-DIETHOXYCARBONYL-1,4-DIHYDROPYRIDINE-4- CARBOXAMIDE)GULTARIC ACID,DISODIUM SALT AND MANUFACTURE
Document Type and Number:
Japanese Patent JPS5993049
Kind Code:
A
Abstract:
2-(2,6-dimethyl-3,5-diethoxycarbonyl-1,4-dihydropyridine-4-carboxamide) glutaric acid of formula I and its disodium salt of formula II (I) (II) Said acid is obtained from glutaminic acid and dimethyl 3,5-diethoxycarbonyl-1,4-dihydroisonicotic acid. For obtaining disodium salt, said acid is reacted with a caustic soda solution. These compounds possess antiarrhythmic activity.
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Inventors:
EGIRUSU ARUBIDOUITSUCHI BISENI
GUNAARU YANOUITSUCHI DOUBUURU
YAN RIHARUDOUITSUCHI URUDORIKI
MARISU MARUGEROUITSUCHI BEBERI
AGURISU ADORUFUOUITSUCHI KIMEN
EFUGENII WASHIRIEUITSUCHI IWAN
GUNAARU YANOUITSUCHI DOUBUURU
YAN RIHARUDOUITSUCHI URUDORIKI
MARISU MARUGEROUITSUCHI BEBERI
AGURISU ADORUFUOUITSUCHI KIMEN
EFUGENII WASHIRIEUITSUCHI IWAN
Application Number:
JP19895383A
Publication Date:
May 29, 1984
Filing Date:
October 24, 1983
Export Citation:
Assignee:
INST ORUGANIICHIESUKAGO SHINTE
International Classes:
A61K31/4422; A61K31/455; A61P9/06; C07D211/90; (IPC1-7): A61K31/455; C07D211/90
Attorney, Agent or Firm:
Kazuo Sato
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