Title:
(±)2-(ジメチルアミノ)-1-{〔O-(m-メトキシフェネチル)フェノキシ〕メチル}エチル水素サクシナート塩酸塩のI形結晶とII形結晶の混晶の製造法
Document Type and Number:
Japanese Patent JP4849374
Kind Code:
B2
Abstract:
To provide a method for producing a mixed crystal of type I crystal and type II crystal of (±)2-(dimethylamino)-1-ä[O-(m-methoxyphenethyl)phenoxy]methyl}ethyl hydrogen succinate hydrochloride useful as a pharmaceutical product.
(±)2-(Dimethylamino)-1-ä[O-(m-methoxyphenethyl)phenoxy]methyl}ethyl hydrogen succinate hydrochloride is recrystallized from or suspended in acetonitrile, to form a mixed crystal of type I crystal and type II crystal of (±)2-(dimethylamino)-1-ä[O-(m-methoxyphenethyl)phenoxy]methyl}ethyl hydrogen succinate hydrochloride.
COPYRIGHT: (C)2009,JPO&INPIT
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Inventors:
Tetsuya Oyama
Ryuichi Omote
Shin Ikeda
Suzuki Yoshinobu
Ryuichi Omote
Shin Ikeda
Suzuki Yoshinobu
Application Number:
JP2007133384A
Publication Date:
January 11, 2012
Filing Date:
May 18, 2007
Export Citation:
Assignee:
Dnp Fine Chemical Co., Ltd. Fukushima
International Classes:
C07C213/10; C07C219/06; A61K31/225; A61P1/04; A61P7/02; A61P9/08; A61P9/10; A61P25/02; A61P29/00
Domestic Patent References:
| JP2007217333A | ||||
| JP2008285445A |