Title:
2-イミノイミダゾール誘導体(2)
Document Type and Number:
Japanese Patent JP4251872
Kind Code:
B2
Abstract:
The present invention relates to a 2-iminopyrrolidine derivative selected from the group consisting of 1-(3-tert-butyl-4-methoxy-5-morpholino-phenyl)-2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydro-isoindol-2-yl)-ethanone; 1-{3-tert-butyl-5-[4-(2-hydroxy-acetyl)piperazin-1-yl]-4-methoxyphenyl}-2-(5,6-diethoxy-7-fluoro-1-imino-1,3-diyhdro-isoindol-2-yl)-ethanone; ethyl (4-{3-tert-butyl-5-[2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydro-isoindol-2-yl)-acetyl]-2-methoxy-phenyl}piperazin-1-yl)-acetate; 1-(3-tert-butyl-4-methoxy-5-piperazin-1-yl-phenyl)-2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydro-isoindol-2-yl)-ethanone, and (4-{3-tert-butyl-5-[2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydro-isoindol-2-yl)-acetyl]-2-methoxy-phenyl}-piperazin-1-yl)-acetic acid; and salts thereof.
Inventors:
Shuichi Suzuki
Makoto Kotake
Mitsuaki Miyamoto
Tetsuya Kawahara
Shoji Kajiwara
Hishinuma Uharu
Kazuo Okano
Shuhei Miyazawa
Clark richard
Fumihiro Ozaki
Nobuaki Sato
Masanobu Shinoda
Atsushi Kamata
Takashi Tsukada
Fumiyoshi Matsuura
Yoshimitsu Naoe
Taro Terauchi
Yoshiaki Ohashi
Osamu Ito
Hiromu Tanaka
Warrior Takashi
Motoharu Kogushi
Kawada Riki
Toshiyuki Matsuoka
Kobayashi Hiroko
Kenichi Chiba
Kimura Akibun
Naoto Ono
Makoto Kotake
Mitsuaki Miyamoto
Tetsuya Kawahara
Shoji Kajiwara
Hishinuma Uharu
Kazuo Okano
Shuhei Miyazawa
Clark richard
Fumihiro Ozaki
Nobuaki Sato
Masanobu Shinoda
Atsushi Kamata
Takashi Tsukada
Fumiyoshi Matsuura
Yoshimitsu Naoe
Taro Terauchi
Yoshiaki Ohashi
Osamu Ito
Hiromu Tanaka
Warrior Takashi
Motoharu Kogushi
Kawada Riki
Toshiyuki Matsuoka
Kobayashi Hiroko
Kenichi Chiba
Kimura Akibun
Naoto Ono
Application Number:
JP2002585394A
Publication Date:
April 08, 2009
Filing Date:
April 19, 2002
Export Citation:
Assignee:
Eisai R & D Management Co., Ltd.
International Classes:
C07D233/88; A61K31/403; A61K31/4035; A61K31/4178; A61K31/4184; A61K31/422; A61K31/437; A61K31/454; A61K31/496; A61K31/5377; A61K31/538; A61P7/02; A61P9/00; A61P9/10; A61P9/12; A61P11/00; A61P11/06; A61P13/12; A61P19/10; A61P25/00; A61P29/00; A61P35/00; A61P43/00; C07D207/22; C07D207/24; C07D207/263; C07D207/267; C07D207/34; C07D209/44; C07D209/52; C07D209/54; C07D209/62; C07D209/96; C07D213/73; C07D213/74; C07D233/46; C07D233/66; C07D233/90; C07D235/30; C07D249/14; C07D261/14; C07D401/04; C07D401/06; C07D401/10; C07D401/12; C07D403/04; C07D403/06; C07D403/10; C07D403/12; C07D405/06; C07D409/04; C07D409/06; C07D409/10; C07D413/06; C07D413/10; C07D413/12; C07D413/14; C07D417/06; C07D417/10; C07D471/04; C07D487/04; C07D491/10; C07D498/04; C07D521/00; C07D207/26; A61K; A61P; C07D
Foreign References:
| WO1998000408A1 | ||||
| US3904395 | ||||
| US3887577 |
Other References:
Khimiya Geterotsiklicheskikh Soedinenii,1971年,7(12),pp.1692-1694
Attorney, Agent or Firm:
Yoshiki Hasegawa
Shiro Terasaki
Kimoto
Shiro Terasaki
Kimoto