Title:
癌の処置のためのチェックポイントキナーゼCDS1(CHK2)インヒビターとしての2-フェニル-ベンズイミダゾールおよび2-フェニル-イミダゾ-‘4,5!-ピリジン誘導体
Document Type and Number:
Japanese Patent JP4726235
Kind Code:
B2
Abstract:
2-Aryl substituted benzimidazoles and imidazo[4,5]pyridines are disclosed as inhibitors of Cds1 and useful as adjuvants to chemotherapy or radiation therapy in the treatment of cancer.
Inventors:
Americus, Michael Kay
Kristen El, Oriente
Axe, Frank You
Breiten Busier, Jay Guy
Kristen El, Oriente
Axe, Frank You
Breiten Busier, Jay Guy
Application Number:
JP2006513065A
Publication Date:
July 20, 2011
Filing Date:
April 16, 2004
Export Citation:
Assignee:
JANSSEN PHARMACEUTICA NAAMLOZE VENNOOTSCHAP
International Classes:
C07D235/18; A61K31/4184; A61K31/454; A61K31/4745; A61P43/00; C07D235/22; C07D401/10; C07D401/12; C07D403/12; C07D405/10; C07D405/12; C07D409/10; C07D409/12; C07D471/02; A61K31/4439; A61K31/4709; A61K31/496; A61P35/00
Foreign References:
| WO2002072090A1 | ||||
| WO2003028724A1 |
Other References:
J. Med. Chem.,2000年,vol.43, no.22,p.4084-4097
Attorney, Agent or Firm:
Patent business corporation Odashima patent office