Title:
2’-置換ヌクレオシド誘導体およびウイルス疾患の処置のためのその使用方法
Document Type and Number:
Japanese Patent JP2014515023
Kind Code:
A
Abstract:
The present invention relates to 2′-Substituted Nucleoside Derivatives of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, B, X, R1, R2 and R3 are as defined herein. The present invention also relates to compositions comprising at least one 2′-Substituted Nucleoside Derivative, and methods of using the 2′-Substituted Nucleoside Derivatives for treating or preventing HCV infection in a patient.
Inventors:
Gili Yabal Laban, Vinay
Nyoroji, F. Yogyoji
Bogen, Stephan
Bhima, Visijar
Veneto, frank
Kelex, Anjiera
Arasatsupan, ashiyoku
Pitsarnitsski, Dmitri
Dan, Kang
Debace, Ian
Olsen, David, Bee
Stanford, Andrew
Batka, Joseph, Pee
Nyoroji, F. Yogyoji
Bogen, Stephan
Bhima, Visijar
Veneto, frank
Kelex, Anjiera
Arasatsupan, ashiyoku
Pitsarnitsski, Dmitri
Dan, Kang
Debace, Ian
Olsen, David, Bee
Stanford, Andrew
Batka, Joseph, Pee
Application Number:
JP2014505234A
Publication Date:
June 26, 2014
Filing Date:
April 11, 2012
Export Citation:
Assignee:
Merck Sharp & Dohme Corp.
International Classes:
C07H19/073; A61K31/7056; A61K31/7068; A61K31/7072; A61K38/21; A61K45/00; A61K47/48; A61P1/16; A61P31/14; A61P43/00; C07H19/10; C07H19/11; C07H19/16; C07H19/20; C07H19/213
Domestic Patent References:
| JP2004533401A | 2004-11-04 |
Foreign References:
| WO2006116557A1 | 2006-11-02 | |||
| US20100297079A1 | 2010-11-25 | |||
| US20100104532A1 | 2010-04-29 | |||
| US20100021425A1 | 2010-01-28 |
Attorney, Agent or Firm:
Yoshikazu Iwase
Makoto Ono
Kenkyo Kanayama
Mitsuaki Tsubokura
Kazuki Shigemori
Kenji Ando
Yasufumi Shiroyama
Makoto Ono
Kenkyo Kanayama
Mitsuaki Tsubokura
Kazuki Shigemori
Kenji Ando
Yasufumi Shiroyama