Title:
【発明の名称】2-アミノ-1,3-プロパンジオール化合物および免疫抑制剤
Document Type and Number:
Japanese Patent JP2579602
Kind Code:
B2
Abstract:
A 2-amino-1,3-propanediol compound represented by general formula (I) or a pharmaceutically acceptable salt thereof, and an immunosuppressant containing the same as the active ingredient. In said formula R represents optionally substituted linear or branched carbon chain, optionally substituted aryl or optionally substituted cycloalkyl; and R<2>, R<3>, R<4> and R<5>, which may be the same or different from one another, represent each hydrogen, alkyl, aralkyl, acyl or alkoxycarbonyl. The compound is immunodepressant and useful as an inhibitor against rejection in organ or bone marrow transplantation, as a preventive or remedy for autoimmune diseases and so forth, or a reagent in the medical and pharmaceutical fields.
Inventors:
FUJITA TETSURO
SASAKI SHIGEO
YONEDA MASAHIKO
MISHINA TADASHI
ADACHI KUNITOMO
CHIBA KENJI
SASAKI SHIGEO
YONEDA MASAHIKO
MISHINA TADASHI
ADACHI KUNITOMO
CHIBA KENJI
Application Number:
JP50984594A
Publication Date:
February 05, 1997
Filing Date:
October 18, 1993
Export Citation:
Assignee:
YOSHITOMI SEIYAKU KK
TAITO KK
TAITO KK
International Classes:
A01N33/02; A01N43/40; A01N43/60; A01N57/00; C07C215/10; C07C215/18; C07C215/20; C07C215/24; C07C215/26; C07C215/28; C07C215/34; C07C215/42; C07C215/54; C07C215/56; C07C215/68; C07C217/28; C07C217/30; C07C217/34; C07C217/48; C07C217/52; C07C217/64; C07C217/72; C07C217/76; C07C219/06; C07C219/24; C07C219/30; C07C225/04; C07C225/06; C07C225/10; C07C225/14; C07C225/16; C07C229/22; C07C229/38; C07C229/46; C07C233/18; C07C233/31; C07C233/35; C07C233/36; C07C233/41; C07C233/43; C07C233/47; C07C237/06; C07C237/24; C07C237/30; C07C251/38; C07C271/20; C07C271/24; C07C271/28; C07C323/25; C07C323/30; C07C323/32; C07C323/34; C07C323/41; C07D207/06; C07D207/09; C07D207/325; C07D207/335; C07D211/14; C07D211/26; C07D213/38; C07D213/40; C07D233/54; C07D237/08; C07D239/26; C07D241/12; C07D261/08; C07D263/32; C07D265/30; C07D275/02; C07D277/28; C07D279/12; C07D295/13; C07D295/135; C07D307/52; C07D309/32; C07D317/28; C07D333/20; C07D521/00; C07D207/32; (IPC1-7): C07C215/10; A61K31/13; A61K31/195; A61K31/215; A61K31/24; C07C215/28; C07C217/08; C07C219/06; C07C219/20; C07C219/22; C07C225/06; C07C229/08; C07C233/18; C07C251/38; C07C317/32; C07C323/25; C07D211/26; C07D213/38; C07D213/40; C07D319/06; C07D333/20
Domestic Patent References:
| JPS632904A | 1988-01-07 | |||
| JPS57156459A | 1982-09-27 | |||
| JPS58101108A | 1983-06-16 | |||
| JPH04173723A | 1992-06-22 | |||
| JPS6343140A | 1988-02-24 | |||
| JPH0469320A | 1992-03-04 | |||
| JPS5154565A | 1976-05-13 |
Attorney, Agent or Firm:
Takashima Hajime
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