Title:
２－アミノピリミジン化合物及びその使用
Document Type and Number:
Japanese Patent JP2022538493
Kind Code:
A
Abstract:
本発明は、下記一般式Ｉの２－アミノピリミジン化合物及びその製薬上許容可能な塩、溶媒和物又はプロドラッグ、これらの製造方法及び前記化合物を含有する医薬組成物に関し、置換基Ｒ１、Ｒ２、Ｒ３、Ｒ４、Ｘ、Ｙ、Ｚ、Ｑ、ｍ、ｎは明細書に与えられる意義を有する。本発明は、下記一般式Ｉの化合物の、悪性血液疾患とその他の増殖性疾患を治療及び／又は予防する薬物の製造における使用にも関する。TIFF2022538493000023.tif38161
Inventors:
Zhao, Yangfang
Re, insulation
Chin, Minze
Hou, Yunlei
Liu, Yajin
gon, pin
Re, insulation
Chin, Minze
Hou, Yunlei
Liu, Yajin
gon, pin
Application Number:
JP2022500082A
Publication Date:
September 02, 2022
Filing Date:
July 01, 2020
Export Citation:
Assignee:
Shenyang Pharmaceutical University
International Classes:
C07D239/48; A61K31/506; A61K31/5377; A61P7/00; A61P35/00; A61P35/02; A61P43/00; C07D239/50; C07D239/95; C07D401/04; C07D401/12; C07D403/04; C07D403/12; C07D495/04
Domestic Patent References:
| JP2016520098A | 2016-07-11 | |||
| JP2015523383A | 2015-08-13 | |||
| JP2014506592A | 2014-03-17 | |||
| JP2013527175A | 2013-06-27 | |||
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Foreign References:
| KR20180137057A | 2018-12-27 | |||
| WO2016130920A2 | 2016-08-18 | |||
| WO2006105056A2 | 2006-10-05 | |||
| CN105461694A | 2016-04-06 |
Other References:
REGISTRY（STN）[ONLINE], JPN7023000917, ISSN: 0005008604
OHNO, SACHIO ET AL.: "Synthesis and hypoglycemic activity of 7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidine derivatives and re", CHEMICAL & PHARMACEUTICAL BULLETIN, vol. 34(10),, JPN6023008824, 1986, pages 4150 - 4165, ISSN: 0005008603
OHNO, SACHIO ET AL.: "Synthesis and hypoglycemic activity of 7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidine derivatives and re", CHEMICAL & PHARMACEUTICAL BULLETIN, vol. 34(10),, JPN6023008824, 1986, pages 4150 - 4165, ISSN: 0005008603
Attorney, Agent or Firm:
Patent Attorney Corporation Tsukuni
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