Title:
ブラジキニン受容体アンタゴニストとして有用な2-アリール-プロピオンアミド誘導体およびそれらを含有する医薬組成物
Document Type and Number:
Japanese Patent JP2013509376
Kind Code:
A
Abstract:
(R,S) 2-aryl-propionamide derivatives, or their single enantiomers (R) and (S) are disclosed useful in the treatment or prevention of symptoms and disorders such as pain and inflammation associated with the bradykinin B1 pathway.
Inventors:
Beckali, Andrea
Aramini, Andrea
Biantoni, Gianluca
Mauriconi, Alessio
Aramini, Andrea
Biantoni, Gianluca
Mauriconi, Alessio
Application Number:
JP2012535821A
Publication Date:
March 14, 2013
Filing Date:
October 28, 2010
Export Citation:
Assignee:
Dompe Sochieta Pell Azioni
International Classes:
C07C233/40; A61K31/164; A61K31/341; A61K31/36; A61K31/381; A61K31/40; A61K31/415; A61K31/4155; A61K31/4196; A61K31/421; A61K31/422; A61K31/426; A61K31/427; A61K31/4402; A61K31/4409; A61K31/4439; A61K31/4468; A61K31/454; A61K31/4709; A61K31/505; A61K31/506; A61K31/5377; A61P1/02; A61P1/04; A61P1/16; A61P3/10; A61P9/00; A61P9/04; A61P11/00; A61P11/02; A61P11/06; A61P11/08; A61P13/10; A61P15/00; A61P17/00; A61P17/02; A61P17/06; A61P19/00; A61P19/02; A61P19/10; A61P25/00; A61P25/04; A61P25/06; A61P25/08; A61P25/16; A61P25/28; A61P29/00; A61P31/04; A61P35/00; A61P37/00; A61P43/00; C07C235/34; C07C235/78; C07C237/20; C07C271/22; C07C275/24; C07C309/66; C07C311/39; C07D207/09; C07D207/50; C07D211/58; C07D213/40; C07D213/74; C07D231/12; C07D239/42; C07D249/08; C07D263/48; C07D277/20; C07D277/42; C07D277/44; C07D295/12; C07D307/50; C07D307/52; C07D317/66; C07D333/22; C07D401/12; C07D409/12; C07D413/12; C07D417/12; C07D417/14
Domestic Patent References:
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| JP2012526062A | 2012-10-25 | |||
| JPS5976045A | 1984-04-28 | |||
| JPH06234763A | 1994-08-23 | |||
| JP2001511781A | 2001-08-14 | |||
| JP2000034269A | 2000-02-02 | |||
| JP2002533438A | 2002-10-08 | |||
| JP2005170939A | 2005-06-30 | |||
| JP2008543313A | 2008-12-04 |
Foreign References:
| US20060111392A1 | 2006-05-25 | |||
| WO1995032943A1 | 1995-12-07 | |||
| WO2009075874A1 | 2009-06-18 | |||
| US3729475A | 1973-04-24 |
Other References:
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 11, no. 1, JPN6014045863, 1976, pages 7 - 12, ISSN: 0002929631
CHEMICAL BIOLOGY & DRUG DESIGN., vol. 69, JPN6014045864, 2007, pages 222 - 226, ISSN: 0002929632
IL FARMACO, vol. 54, JPN6015031973, 1999, pages 600 - 610, ISSN: 0003132279
IL FARMACO - ED. SC., vol. Vol. 35, fasc. 8, JPN6015031978, 1980, pages 684 - 690, ISSN: 0003132280
JOURNAL OF PHARMACY AND PHARMACOLOGY, vol. 9, no. 1, JPN6015031975, 1957, pages 20 - 28, ISSN: 0003132277
LATVIJAS PSR ZINATNU AKADEMIJAS VESTIS, KIMIJAS SERIJA, JPN6015031976, 1976, pages 65 - 68, ISSN: 0003132278
CHEMICAL BIOLOGY & DRUG DESIGN., vol. 69, JPN6014045864, 2007, pages 222 - 226, ISSN: 0002929632
IL FARMACO, vol. 54, JPN6015031973, 1999, pages 600 - 610, ISSN: 0003132279
IL FARMACO - ED. SC., vol. Vol. 35, fasc. 8, JPN6015031978, 1980, pages 684 - 690, ISSN: 0003132280
JOURNAL OF PHARMACY AND PHARMACOLOGY, vol. 9, no. 1, JPN6015031975, 1957, pages 20 - 28, ISSN: 0003132277
LATVIJAS PSR ZINATNU AKADEMIJAS VESTIS, KIMIJAS SERIJA, JPN6015031976, 1976, pages 65 - 68, ISSN: 0003132278
Attorney, Agent or Firm:
Shinjiro Ono
Yasushi Kobayashi
Hiroyuki Tomita
Osamu Hoshino
Akiko Yamaguchi
Yasushi Kobayashi
Hiroyuki Tomita
Osamu Hoshino
Akiko Yamaguchi