糖尿病および脂質障害用の2-アリールオキシ-2-アリールアルカン酸類

Japanese Patent JP2004521124

A

A class of 2-aryloxy-2-arylalkanoic acids comprises compounds that are potent agonists of PPAR alpha and/or gamma, and are therefore useful in the treatment, control or prevention of non-insulin dependent diabetes mellitus (NIDDM), hyperglycemia, dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, atherosclerosis, obesity, vascular restenosis, inflammation, and other PPAR alpha and/or gamma mediated diseases, disorders and conditions.

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Adams, Alan Day
AJ Bryan
Burger, Joel Pea
Doropinski, The Ames F
Erbrecht, alexander
Riu, Kun
Karen Lam, Matsukunor
See, Quo-Chiyang
Huong Langen, Derek Jei
Chiyo, Khao Chiao

JP2002563891A

July 15, 2004

February 05, 2002

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MERCK & COMPANY INCOPORATED

A61K31/192; A61K31/22; A61K31/366; A61K31/40; A61K31/404; A61K31/41; A61K31/423; A61K31/427; A61K45/00; A61P1/04; A61P1/18; A61P3/04; A61P3/06; A61P3/10; A61P5/28; A61P9/00; A61P9/10; A61P9/12; A61P17/00; A61P17/06; A61P25/28; A61P29/00; A61P35/00; A61P43/00; C07C59/60; C07C59/90; C07D213/55; C07D257/04; C07D261/20; C07D263/32; C07D263/58; C07D413/12; C07D417/12; (IPC1-7): C07C59/60; A61K31/192; A61K31/22; A61K31/366; A61K31/40; A61K31/404; A61K31/41; A61K31/423; A61K31/427; A61K45/00; A61P1/04; A61P1/18; A61P3/04; A61P3/06; A61P3/10; A61P5/28; A61P9/00; A61P9/10; A61P9/12; A61P17/00; A61P17/06; A61P25/28; A61P29/00; A61P35/00; A61P43/00; C07D257/04; C07D261/20; C07D263/58; C07D413/12; C07D417/12

Yoshio Kawaguchi
Akio Ichiiri
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura

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