Title:
2'-FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT
Document Type and Number:
Japanese Patent JP2017075146
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a medicine for the treatment of Flaviviridae virus infections, particularly hepatitis C infections caused by both wild type and mutant strains of HCV.SOLUTION: The present invention provides compounds, compositions, and methods wherein triazinyl nucleosides represented by formula (I), nucleoside phosphates and prodrugs thereof, wherein the 2' position of the nucleoside sugar is substituted with halogen and carbon substituents.SELECTED DRAWING: None
Inventors:
CHO AESOP
KIM CHOUNG U
SAMUEL E METOBO
ADRIAN S RAY
XU JIE
KIM CHOUNG U
SAMUEL E METOBO
ADRIAN S RAY
XU JIE
Application Number:
JP2016207475A
Publication Date:
April 20, 2017
Filing Date:
October 24, 2016
Export Citation:
Assignee:
GILEAD SCIENCES INC
International Classes:
A61K31/53; C07D487/04; A61K31/661; A61K31/663; A61K31/664; A61K31/665; A61K31/7028; A61K31/706; A61P31/12; A61P31/14; A61P43/00; C07F9/09; C07F9/24; C07F9/6571; C07H7/06
Attorney, Agent or Firm:
Shinjiro Ono
Yasushi Kobayashi
Shigeo Takeuchi
Osamu Yamamoto
Hiroko Ejiri
Yasushi Kobayashi
Shigeo Takeuchi
Osamu Yamamoto
Hiroko Ejiri
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