Title:
2-PIPERIDONE DERIVATIVE AS PROSTAGLANDIN AGONIST
Document Type and Number:
Japanese Patent JP2010047580
Kind Code:
A
Abstract:
To provide a compound usable for treating diseases, e.g. osteopathy, especially osteoporosis, in mammals, treatable by administering a prostaglandin EP4 receptor agonist; to provide a pharmaceutical composition containing the compound; and to provide a method for using the pharmaceutical composition.
The compound is represented by formula (I). Pharmaceutically acceptable salts, solvates, prodrugs, single isomers or a racemic or non-racemic mixture of isomers thereof, are also provided.
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Inventors:
ELWORTHY TODD RICHARD
Application Number:
JP2009230447A
Publication Date:
March 04, 2010
Filing Date:
October 02, 2009
Export Citation:
Assignee:
HOFFMANN LA ROCHE
International Classes:
C07D211/76; A61K31/45; A61P19/00; A61P19/10; A61P43/00
Domestic Patent References:
| JPS51143663A | 1976-12-10 | |||
| JPS59144756A | 1984-08-18 | |||
| JPS4985049A | 1974-08-15 | |||
| JP2001181210A | 2001-07-03 |
Foreign References:
| WO2002024647A1 | 2002-03-28 | |||
| WO2002042268A2 | 2002-05-30 | |||
| US4238623A | 1980-12-09 |
Other References:
JPN6008057318; Ｊｏｕｒｎａｌ ｏｆ Ｈｅｔｅｒｏｃｙｃｌｉｃ Ｃｈｅｍｉｓｔｒｙ Ｖｏｌ．２６， Ｎｏ．３, 1989, ｐ．７２５-７２８
Attorney, Agent or Firm:
Hajime Tsukuni
Koshiro Tsukuda
Fusayuki Saito
Yuichi Okazaki
Koshiro Tsukuda
Fusayuki Saito
Yuichi Okazaki