Title:
The 2 ring type aza-compound as a muscarine M1 receptor operation medicine
Document Type and Number:
Japanese Patent JP6204476
Kind Code:
B2
Abstract:
This invention relates to compounds (Formula (1)) that are agonists of the muscarinic M1 receptor and which are useful in the treatment of muscarinic M1 receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds provided are of formula where R1-R5, X1, X2 and p are as defined herein.
Inventors:
Brown, Giles Albert
Canesfield, Julie Elaine
Congreave, Miles Stuart
Pickworth, mark
Taehan, Benjamin Gerard
Canesfield, Julie Elaine
Congreave, Miles Stuart
Pickworth, mark
Taehan, Benjamin Gerard
Application Number:
JP2015531649A
Publication Date:
September 27, 2017
Filing Date:
September 18, 2013
Export Citation:
Assignee:
Heptares Therapeutics Limited
International Classes:
C07D451/04; A61K31/4545; A61P25/04; A61P25/18; A61P25/28; A61P29/00; A61P43/00; C07D401/04; C07D451/00
Foreign References:
| WO2006105035A1 |
Attorney, Agent or Firm:
Sakaki Morishita