Title:
21-置換グリコシルステロイド化合物
Document Type and Number:
Japanese Patent JP4610734
Kind Code:
B2
Abstract:
Compounds having the following structure which are provided to provide glyco-steroid compounds having a potent anti-inflammatory effect and little side effects. The above compounds are easily metabolizable steroid compounds substituted at the carbon atom at the 21-position by a substituent -X-(saccharide residue)-Y-CZ-R: wherein X represents -O-, -S- or -NH-; Y represents -O-, -S- or -NH-; Z represents =O or =S; and R represents a bulky functional group excluding a phenyl group.
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| JPS57183783 | MANUFACTURE OF CHOLESTEROL DERIVATIVES |
| JPH05286992 | NEW SIALYLSTEROID |
Inventors:
Takayuki Ishii
Nunomura Shigeki
Masaaki Numata
Masami Iida
Noriko Tanaka
Chiaki Sato
Nunomura Shigeki
Masaaki Numata
Masami Iida
Noriko Tanaka
Chiaki Sato
Application Number:
JP2000536734A
Publication Date:
January 12, 2011
Filing Date:
March 19, 1999
Export Citation:
Assignee:
Mikasa Pharmaceutical Co., Ltd.
International Classes:
C07J17/00; A61K31/58; A61P11/06; A61P17/00; A61P19/02; A61P29/00
Domestic Patent References:
| JPH11269194A | 1999-10-05 | |||
| JPH08505616A | 1996-06-18 |
Foreign References:
| GB1047542A | 1966-11-09 | |||
| WO1995009177A1 | 1995-04-06 | |||
| GB1059548A | 1967-02-22 |
Other References:
JPN6009049185, ＨＡＲＲＥＵＳ，Ａ． ｅｔ ａｌ．, "Ｓｔｅｒｅｏｓｅｌｅｃｔｉｖｅ ｇｌｙｃｏｓｙｌａｔｉｏｎ ｏｆ ｓｔｅｒｏｉｄ ａｌｃｏｈｏｌｓ ｕｓｉｎｇ ２，３，４，６−ｔｅｔｒａ−Ｏ−ｐｉｖａｌｏｙｌ−α−Ｄ−ｇｌｕｃｏｐｙｒａｎｏｓｙｌ", Ｌｉｅｂｉｇｓ Ａｎｎａｌｅｎ ｄｅｒ Ｃｈｅｍｉｅ, 1986, Ｎｏ．４, ｐ．７１７−７３０
JPN6010015450, Ｊ． Ｓｔｅｒｏｉｄ Ｂｉｏｃｈｅｍ．, 1982, Ｖｏｌ．１７, ｐｐ．７０３−７０６
JPN6010015450, Ｊ． Ｓｔｅｒｏｉｄ Ｂｉｏｃｈｅｍ．, 1982, Ｖｏｌ．１７, ｐｐ．７０３−７０６
Attorney, Agent or Firm:
Takehiko Saito
Yasuyuki Hata
Yasuyuki Hata