２３−イン−ビタミンＤ３誘導体

Title:

２３−イン−ビタミンＤ３誘導体

Document Type and Number:

Japanese Patent JP5738307

Kind Code:

B2

Abstract:

To provide a novel vitamin D 3 derivative useful as a therapeutic agent for osteoporosis. Provided is a vitamin D 3 derivative represented by the following formula (1) or a medicinally acceptable solvate thereof: wherein R 1 represents a hydrogen atom, an alkyl group having 1 to 6 carbon atoms, an alkylcarbonyloxyalkyl group with each alkyl having 1 to 6 carbon atoms, or an arylcarbonyloxyalkyl group with the aryl having 6 to 10 carbon atoms and the alkyl having 1 to 6 carbon atoms; R 2 represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms or, together with the other R 2 and the carbon atom to which they are bound to, may form a cyclic alkyl group having 3 to 6 carbon atoms; R 3 represents an alkyl group having 1 to 6 carbon atoms or, together with the other R 3 and the carbon atom to which they are bound to, may form a cyclic alkyl group having 3 to 6 carbon atoms; X represents an oxygen atom or a methylene group; and n represents an integer of 1 or 2.

Inventors:

Hiroshi Saito
Komiyama Masato
Ochiai Sharp
Kenichiro Takagi
Takayuki Senda
Mariko Fujita
Keiichiro Imaizumi
Toshiyuki Kaneko

Application Number:

JP2012540840A

Publication Date:

June 24, 2015

Filing Date:

October 24, 2011

Export Citation:

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Assignee:

Teijin Pharma Limited

International Classes:

C07C401/00; A61K31/593; A61P19/10; C07F7/18

Domestic Patent References:

JP2009013154A	2009-01-22
JP2009256361A	2009-11-05
JP2009013154A	2009-01-22

Foreign References:

WO2001062723A1	2001-08-30
WO1999052863A1	1999-10-21
WO1999003829A1	1999-01-28
WO2001062723A1	2001-08-30

Attorney, Agent or Firm:

Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Ryotaro Takei
Kazumi Nakamura

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