Title:
バニロイド-1受容体(VR1)の機能を調節する2,3-置換縮合二環式ピリミジン4-(3H)-オン
Document Type and Number:
Japanese Patent JP2009536608
Kind Code:
A
Abstract:
The use of a compound of formula (I): for the manufacture of a medicament for the treatment of conditions ameliorated by the modulation of the function of the vanilloid-1 receptor (VR1, also known as TRPV1).
Inventors:
Brown, Rebecca Elizabeth
Hanf Ellies, Alexander Chillards
Rogers, Rogers
Bayliss, Tracy
AJ Bryan
Moise, Christopher Richard
Holingworth, Gregory Jiyoung
Bram, Challes A
Chiyon, Xiaochiyan
Baktar Beech Yaram, Large Yago Pearl
Kapito Stay, Scott
Hanf Ellies, Alexander Chillards
Rogers, Rogers
Bayliss, Tracy
AJ Bryan
Moise, Christopher Richard
Holingworth, Gregory Jiyoung
Bram, Challes A
Chiyon, Xiaochiyan
Baktar Beech Yaram, Large Yago Pearl
Kapito Stay, Scott
Application Number:
JP2008511329A
Publication Date:
October 15, 2009
Filing Date:
May 10, 2006
Export Citation:
Assignee:
Merck Sharp End Dome Limited
Nyurogen Corporation
Nyurogen Corporation
International Classes:
C07D473/30; A61K31/519; A61K31/522; A61K31/5377; A61P1/00; A61P1/04; A61P3/04; A61P11/00; A61P11/02; A61P11/06; A61P19/06; A61P37/04; A61P43/00; C07D513/04
Domestic Patent References:
| JPH1112255A | 1999-01-19 | |||
| JPH11158072A | 1999-06-15 | |||
| JP2004528312A | 2004-09-16 |
Foreign References:
| WO2006047516A2 | 2006-05-04 | |||
| WO2004037176A2 | 2004-05-06 |
Other References:
JPN5008006060; ＮＩＥＬＳＥＮ: ＴＥＴＲＡＨＥＤＲＯＮ Ｖ３８ Ｎ１０, 1982, Ｐ１４３５-１４４１
JPN5008006061; ＭＯＨＡＮ: ＴＥＴＲＡＨＥＤＲＯＮ ＬＥＴＴＥＲＳ Ｖ４５ Ｎ３１, 20040726, Ｐ６０７５-６０７７, ＥＬＳＥＶＩＥＲ
JPN5008006061; ＭＯＨＡＮ: ＴＥＴＲＡＨＥＤＲＯＮ ＬＥＴＴＥＲＳ Ｖ４５ Ｎ３１, 20040726, Ｐ６０７５-６０７７, ＥＬＳＥＶＩＥＲ
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura