Title:
2*33DIHYDROOIMIDAZO*2*11B*BENZOTHIAZOLES
Document Type and Number:
Japanese Patent JPS567794
Kind Code:
A
Abstract:
Compounds of formula
and the salts of formula
wherein:
R<1> and R<3> are hydrogen and alkyl;
R<2> and R<4> are hydrogen, alkyl, aryl, aralkyl, alkyloxyl alkyl or aryloxyl alkyl;
R<5>, R<6>, R<7> and R<8> are hydrogen; halo; nitro; alkyl; cycloalkyl; hydroxy; alkyloxy; aryloxy; alpha -hydroxyaryl-methyl; amino; mono- and dialkyl-amino; mono-, di- and trihalo alkyl-amino; alkenylamino; alkynylamino; (aryl alkyl) amino; (alkyloxy alkyl)amino; (hydroxy alkyl)amino; (aryloxy alkyl)amino; (mono- and di(alkyl)amino-alkyl)amino; alkanoyl-amino; N-(alkyl)-alkanoylamino; aminocarbonylamino; (1-alkyl-4-piperidinyl)amino; cycloalkylamino wherein said cycloalkyl represents a mono-, bi-, tri- or tetracyclic hydrocarbon radical having from 3 to 10 carbon atoms; and a radical of the formula
wherein R<1><0> is hydrogen, alkyl, alkenyl and alkynyl; or, when taken together R<5> and R<6>, R<6> and R<7>, or R<7> and R<8> may form a tri- or tetramethylene bridge or complete a fused benzene nucleus; R<9> is alkyl, alkenyl, alkynyl and aryl alkyl; and X is a pharmaceutically acceptable anion and n represents the valency of the anion, display monoamine oxidase inhibiting properties.
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Inventors:
BUIKUTORU SHIPIDO
Application Number:
JP8221580A
Publication Date:
January 27, 1981
Filing Date:
June 19, 1980
Export Citation:
Assignee:
JANSSEN PHARMACEUTICA NV
International Classes:
A61K31/425; A61P25/00; A61P25/24; A61P25/26; C07C205/12; C07C331/28; C07C335/16; C07D277/82; C07D277/84; C07D513/04; (IPC1-7): A61K31/425; C07D513/04
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