Title:
２，４−ジアミノフェノール誘導体、及び、タウ及び／又はアミロイドβの凝集阻害剤
Document Type and Number:
Japanese Patent JP6962572
Kind Code:
B2
Abstract:
[Problem] To provide an agent for inhibiting aggregation of tau and/or amyloid β. [Solution] A compound represented by formula (I) or a salt thereof. This compound is used in therapy, diagnosis, and symptom alleviation and in prevention of tauopathy and/or amyloidosis caused by Aβ aggregation.
Inventors:
Tomohiro Miyasaka
Inoue Zen Ladies
Hachiro Sugimoto
Yasuo Ihara
Takami Mako
Nobuhara Mika
Yuki Fujita
Inoue Zen Ladies
Hachiro Sugimoto
Yasuo Ihara
Takami Mako
Nobuhara Mika
Yuki Fujita
Application Number:
JP2018505849A
Publication Date:
November 05, 2021
Filing Date:
March 08, 2017
Export Citation:
Assignee:
School corporation Doshisha
International Classes:
C07D211/14; A61K31/136; A61K31/137; A61K31/4025; A61K31/407; A61K31/4453; A61K31/454; A61K31/4545; A61K31/472; A61K31/496; A61K31/506; A61K31/5377; A61K31/55; A61K31/551; A61P25/28; C07D209/52; C07D211/22; C07D211/32; C07D213/74; C07D239/42; C07D243/08; C07D295/135; C07D295/185; C07D295/192; C07D295/205; C07D295/215; C07D307/68; C07D333/20; C07D487/08
Domestic Patent References:
| JP2011518119A |
Foreign References:
| WO1998020864A1 | ||||
| DE1058514B |
Other References:
HUIJBREGTS, M. A. J. ET AL.,Human- Toxicological Effect and Damage Factors of Carcinogenic and Noncarcinogenic Chemicals for Life Cycle Impact Assessment,INTEGRATED ENVIRONMENTAL ASSESSMENT AND MANAGEMENT,2005年,vol. 1, no. 3,pages 181 - 244
REGISTRY[online],1988年01月23日,[retrieved on 2020.12.11], Retrieved from:STN, CAS登録番号 112441-21-1
REGISTRY[online],1984年11月16日,[retrieved on 2020.12.11], Retrieved from:STN, CAS登録番号 53013-44-8
REGISTRY[online],1988年01月23日,[retrieved on 2020.12.11], Retrieved from:STN, CAS登録番号 112441-21-1
REGISTRY[online],1984年11月16日,[retrieved on 2020.12.11], Retrieved from:STN, CAS登録番号 53013-44-8
Attorney, Agent or Firm:
Maeda patent office