Title:
ホスファチジルイノシトール(PI)3-キナーゼ阻害剤としての2,4,6-三置換ピリミジンおよび癌の治療におけるその使用
Document Type and Number:
Japanese Patent JP2008505876
Kind Code:
A
Abstract:
The invention concerns pyrimidine derivatives of Formula (I) wherein each of Qa, G1, G2, q, R3, r, R4, X1 and Qb have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the production of an anti-proliferative effect in a warm-blooded animal such as man.
Inventors:
Pass, martin
Application Number:
JP2007519883A
Publication Date:
February 28, 2008
Filing Date:
July 07, 2005
Export Citation:
Assignee:
AstraZeneca Activrag
International Classes:
C07D239/42; A61K31/5377; A61P1/04; A61P1/16; A61P3/10; A61P9/00; A61P9/08; A61P9/10; A61P11/00; A61P11/06; A61P13/08; A61P13/12; A61P17/06; A61P19/02; A61P25/00; A61P27/02; A61P29/00; A61P35/00; A61P35/02; A61P35/04; A61P37/08; A61P43/00; C07D401/14; C07D403/04; C07D405/04; C07D405/14; C07D409/04; C07D409/14
Domestic Patent References:
| JP2002114777A | 2002-04-16 | |||
| JP2002522536A | 2002-07-23 | |||
| JP2004509117A | 2004-03-25 |
Foreign References:
| WO2004037812A1 | 2004-05-06 | |||
| WO2002102313A2 | 2002-12-27 | |||
| WO2001083456A1 | 2001-11-08 | |||
| WO2004048365A1 | 2004-06-10 |
Attorney, Agent or Firm:
Kazuo Shamoto
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Takumi Terachi
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Takumi Terachi
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