Title:
26,28-メチレン-1アルファ,25-ジヒドロキシビタミンD2化合物
Document Type and Number:
Japanese Patent JP3681390
Kind Code:
B2
Abstract:
Vitamin D2 analogs in which a cyclopentane ring is introduced into the side chain of 1 alpha ,25-dihydroxyvitamin D2+L, The compounds are characterized by a marked intestinal calcium transport activity while exhibiting much lower activity than 1 alpha ,25-dihydroxyvitamin D3 in their ability to mobilize calcium from bone. Because of their preferential calcemic activity, these compounds would be useful for the treatment of diseases where bone formation is desired, such as osteoporosis.
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Inventors:
Deluca, Hector F.
Nao Nakagawa
Nao Nakagawa
Application Number:
JP51506595A
Publication Date:
August 10, 2005
Filing Date:
October 19, 1994
Export Citation:
Assignee:
WISCONSIN ALUMNI RESEARCH FOUNDATION
International Classes:
A61P3/00; A61P19/10; C07C401/00; C07J9/00; A61K31/59; C07J51/00; (IPC1-7): C07C401/00; A61K31/59; A61P19/10; C07J9/00
Domestic Patent References:
| JP5271183A |
Attorney, Agent or Firm:
Takao Kawasaki
Toshizo Iida
Toshizo Iida