Title:
2,8-二置換ナフチリジン誘導体
Document Type and Number:
Japanese Patent JP2008509151
Kind Code:
A
Abstract:
Disclosed are compounds of formula A: and pharmaceutically acceptable salts thereof, wherein R1, R2, R2', R3, R21, A1, A2, X, and Z are as defined herein. Compounds of formula A are useful in the treatment of diseases and/or conditions related to cell differentiation, such as cancer, inflammation, arthritis, angiogenesis, or the like. Also disclosed are pharmaceutical compositions comprising compounds of the invention and methods of treating the aforementioned conditions using such compounds.
Inventors:
Hanson, Gunner, Jay.
Clothing, Roy, Dove New., Junior.
Balta, Thomas, Yi.
Fan, Kenneth Ho
Clothing, Roy, Dove New., Junior.
Balta, Thomas, Yi.
Fan, Kenneth Ho
Application Number:
JP2007524997A
Publication Date:
March 27, 2008
Filing Date:
August 03, 2005
Export Citation:
Assignee:
Selenex, Inc.
International Classes:
C07D471/04; A61K31/4375; A61K31/444; A61K31/4545; A61K31/496; A61K31/497; A61K31/5377; A61P1/00; A61P1/04; A61P3/10; A61P9/00; A61P11/08; A61P13/12; A61P17/04; A61P17/06; A61P19/02; A61P21/00; A61P21/04; A61P25/04; A61P29/00; A61P35/00; A61P43/00; C07D519/00
Domestic Patent References:
| JP2001525365A | 2001-12-11 |
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda