Title:
3-O脱アシル化モノホスホリルリピドA含有ワクチン組成物
Document Type and Number:
Japanese Patent JP4028593
Kind Code:
B2
Abstract:
Novel vaccine compositions comprising small particles of 3-O-deacylated monophosphoryl lipid A are provided. In particular the particle size are small enough to be filtered through a 220 nm membrane, and in general are below 120 nm. Such vaccine compositions have superior immunological properties.
Inventors:
Auze, Pierre
Boe, pierre
Slawi, Monse
Garcon-Johnson, Natalie Marie-Joseph Claude
Desmon, Pierre
Boe, pierre
Slawi, Monse
Garcon-Johnson, Natalie Marie-Joseph Claude
Desmon, Pierre
Application Number:
JP52064094A
Publication Date:
December 26, 2007
Filing Date:
March 14, 1994
Export Citation:
Assignee:
GLAXOSMITHKLINE BIOLOGICALS S.A.
International Classes:
A61K9/107; A61K9/51; A61K39/39; A61K31/715; A61K38/00; A61K39/12; A61K47/44; A61P31/20; A61P37/04
Foreign References:
| WO1992006113A2 | ||||
| WO1992016556A1 | ||||
| WO1986001826A1 | ||||
| WO1992016231A1 |
Attorney, Agent or Firm:
Aoyama Aoi
Mitsuo Tanaka
Tadayuki Motoyama
Kenji Tomita
Mitsuo Tanaka
Tadayuki Motoyama
Kenji Tomita