3-プロペニルセフェム誘導体 - Shionogi Pharmaceutical Co., Ltd.

Title:

3-プロペニルセフェム誘導体

Document Type and Number:

Japanese Patent JP3928086

Kind Code:

B2

Abstract:

A compound represented by the formula: (I) wherein Acyl represents an acyl group which can be used in the field of ß-lactams; T represents S, SO or O; the group represented by the formula: (Q) represents a heterocyclic group which may be substituted by a substituent other than "-Y¹-Ar¹-Y²-R¹" and has a cationic N atom in the ring; Y¹ and Y² independently represent 1) a single bond, 2) a heteroatom-containing group selected from the group consisting of -NR², -CO-, -NR²CO-, -CONR²-, -NR²CONR³-, -NR²SO₂-, -SO₂NR²-, -NR²SO₂NR³- (where R² and R³ independently represent a hydrogen or a lower alkly), -O-, -S-, -SO- and -SO₂-, or 3) a lower alkylene or lower alkenylene group which may be bound through a heteroatom-containing group as listed in the item 2); Ar¹ represents a single bond, a carbocyclic group which may be substituted or a haterocyclic group which may be substituted; R¹ represents -CONHCN, -C(OH)=NCN or -COOH or a biologically equivalent acidic group thereof; and the wavy line means a cis, trans or a mixture thereof.

Inventors:

Koji Ishikura
Kenji Yamawaki
Yokoo Katsumi
Yonezawa Hideji
Kii Makoto

Application Number:

JP2006523884A

Publication Date:

June 13, 2007

Filing Date:

March 28, 2006

Export Citation:

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Assignee:

Shionogi Pharmaceutical Co., Ltd.

International Classes:

C07D501/24; A61K31/546; A61P31/04; C07D217/16; C07D221/04; C07D487/04; C07D495/04; C07D498/04; C07D513/04

Domestic Patent References:

JP2002518505A
JP7041484A
JP4230289A
JP9110877A

Foreign References:

WO1987003875A1
WO1997037996A1

Attorney, Agent or Firm:

Kenichi Sugita
Hiromitsu Takayama

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