Title:
3-Aminocyclopentane carboxamide derivative
Document Type and Number:
Japanese Patent JP6316835
Kind Code:
B2
Abstract:
Compounds of the formula (I) in which R1, R4, R, X1, X2, X3, X4, q and W have the meanings indicated in Claim 1, are inhibitors of fatty acid synthase, and can be employed, inter alia, for the treatment of diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation.
Inventors:
Zakura Kydis, Christos
Stele, Wolfgang
Reutner, Brigitta
Chodrowski, Paul
Stele, Wolfgang
Reutner, Brigitta
Chodrowski, Paul
Application Number:
JP2015542177A
Publication Date:
April 25, 2018
Filing Date:
October 17, 2013
Export Citation:
Assignee:
Merck Patent Gesellschaft mit beschraenkter Haftung
International Classes:
C07C237/24; A61K31/166; A61K31/18; A61K31/277; A61K31/341; A61K31/343; A61K31/404; A61K31/416; A61K31/4164; A61K31/4184; A61K31/423; A61K31/4245; A61K31/428; A61K31/437; A61K31/4406; A61K31/4409; A61K31/4418; A61K31/4439; A61K31/472; A61K31/496; A61K31/50; A61K31/505; A61K45/00; A61P9/00; A61P25/28; A61P29/00; A61P35/00; A61P35/02; A61P43/00; C07C255/57; C07C311/16; C07C317/44; C07D209/18; C07D213/56; C07D213/81; C07D217/16; C07D231/56; C07D233/64; C07D235/18; C07D237/14; C07D239/26; C07D263/57; C07D271/06; C07D277/66; C07D307/20; C07D307/81; C07D413/04; C07D413/06; C07D413/12; C07D471/04; C07D498/04
Domestic Patent References:
JP2011524893A |
Foreign References:
WO2011048018A1 |
Other References:
KLEY, J. T. et al.,Bioorganic & Medicinal Chemistry Letters,2011年,Vol. 21,pp. 5924-5927
Attorney, Agent or Firm:
Kiyoji Kuzuwa