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Title:
3* (biphenyl *3* Yl) *8 replaced, 8* difluoro *4* hydroxy *1* azaspiro [4.5] Dec *3* Yen *2* ON, and spiro loop-like Ketoenols of which halogen * substitution was done for medical treatment
Document Type and Number:
Japanese Patent JP5905908
Kind Code:
B2
Abstract:
The invention relates to substituted 3-(biphenyl-3-yl)-8,8-difluoro-4-hydroxy-1-azaspiro[4.5]dec-3-en-2-ones of the formula (Ia) for therapeutic purposes, to pharmaceutical compositions and to their use in therapy, in particular for the prophylaxis and therapy of tumor disorders. The invention also relates to novel compounds of the formula (I) in which W, X, Y, Z, A, B, D and G have the meanings given above, to a plurality of processes and intermediates for their preparation, and to their use as pesticides and/or herbicides and/or fungicides. The invention also relates to selectively herbicidal compositions comprising, firstly, the halogen-substituted spirocyclic ketoenols and, secondly, a crop plant compatibility-improving compound. The present invention furthermore relates to the boosting of the action of crop protection compositions comprising, in particular, halogen-substituted spirocyclic ketoenols, through the addition of ammonium salts or phosphonium salts and optionally penetrants, to the corresponding compositions, to processes for producing them and to their application in crop protection as pesticides and/or fungicides and/or for preventing unwanted plant growth.

Inventors:
Brett Chunider, Thomas
Fisher, liner
Leir, Shute Juan
Gutsvailer, Elmer
Gelgens, Ulrich
Heuser-Hahn, Isolde
Heinmann, Ines
Huerste, Arundt
Application Number:
JP2013553914A
Publication Date:
April 20, 2016
Filing Date:
February 14, 2012
Export Citation:
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Assignee:
Bayer Intellectual Property GmbH
International Classes:
C07D209/54; A01N43/08; A01N43/38; A01N47/06; A01P5/00; A01P7/02; A01P7/04; A01P13/00; A61K31/343; A61K31/403; A61P31/04; A61P31/10; A61P33/00; A61P43/00; C07C69/75; C07C229/48; C07C233/52; C07C255/46; C07D235/02; C07D307/94
Domestic Patent References:
JP2000500442A
JP2010511643A
JP5294953A
JP2002513002A
Foreign References:
WO2006046778A1
Other References:
Database REGISTRY,2010年 9月10日,RN 1240529-10-5,Retrieved from STN international [online] ;retrieved on 28 September 2015
Attorney, Agent or Firm:
Yoshikazu Iwase
Makoto Ono
Kenkyo Kanayama
Mitsuaki Tsubokura
Kazuki Shigemori
Kenji Ando
Yasufumi Shiroyama