CXC-ケモカインレセプターリガンドとしての3,4-ジ-置換シクロブテン-1,2-ジオン

Japanese Patent JP5294418

B2

There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.

Arthur G. Taberus
Cynthia Jay Aki
Richard W. Bond
Jumpin Chao
Michael dayer
Johan A. Ferreira
The Hua Chao
Yunon Yu
John Jay. Bardowin
Burned Kaiser
Gerry
Jay Robert Mehrit
Kingray H. Nelson
Laura El. Rocco's

JP2009278869A

September 18, 2013

December 08, 2009

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Merck Sharp & Dohme Corp.

C07C237/30; A61K31/166; C07D249/18; A61K31/167; A61K31/341; A61K31/343; A61K31/36; A61K31/381; A61K31/397; A61K31/40; A61K31/401; A61K31/41; A61K31/415; A61K31/416; A61K31/4192; A61K31/42; A61K31/4245; A61K31/433; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/443; A61K31/445; A61K31/495; A61K31/496; A61K31/506; A61K31/5375; A61K31/54; A61K31/55; A61K45/00; A61P1/04; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P17/06; A61P17/10; A61P19/02; A61P25/28; A61P27/02; A61P31/04; A61P35/00; A61P37/06; A61P37/08; A61P39/02; A61P43/00; C07C225/20; C07C237/44; C07C255/59; C07D205/04; C07D207/08; C07D207/16; C07D211/32; C07D211/60; C07D213/40; C07D213/74; C07D213/76; C07D213/78; C07D213/82; C07D231/44; C07D239/42; C07D239/47; C07D241/04; C07D257/06; C07D261/08; C07D271/06; C07D277/06; C07D277/28; C07D285/06; C07D295/16; C07D307/14; C07D307/52; C07D307/54; C07D307/56; C07D307/78; C07D307/81; C07D317/58; C07D317/62; C07D333/20; C07D333/28; C07D333/36; C07D333/38; C07D333/40; C07D401/04; C07D403/04; C07D405/12; C07D409/04; C07D409/12; C07D413/04; C07D413/12; C07D413/14; C07D417/12; A61K31/425; A61K31/44

JP2005507366A
JP2004521106A
JP2004509070A
JP10509703A
JP10509145A
JP9505296A

Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita

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