Title:
肥満症を治療するためのオピオイド受容体拮抗物質としての4-(5-アミノメチル)-インドール-1-イルメチル)-ベンズアミド誘導体および関連化合物
Document Type and Number:
Japanese Patent JP2007529523
Kind Code:
A
Abstract:
The present invention relates to compounds of formulae (I) and (II) useful as opioid receptor antagonists for the treatment of obesity, wherein p is 0, 1, or 2; y is 0, 1, or 2; and z is 0, 1, or 2; X1 is CH2, CH, or N; to form a indolinyl, indolyl, or benzimidazole ring respectively and including applicable double bonds and/or hydrogen atoms; X2 is CH or N; R1 to R7, R3′, p, y, and z are as defined in the claims.
Inventors:
Dana Ray Benesh
Maria-Jesus Blanco-Pillad
Maria-Jesus Blanco-Pillad
Application Number:
JP2007503959A
Publication Date:
October 25, 2007
Filing Date:
March 09, 2005
Export Citation:
Assignee:
Eli Lilly and Company
International Classes:
C07D209/08; A61K31/404; A61K31/4045; A61P1/00; A61P1/08; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P9/00; A61P9/10; A61P15/10; A61P25/00; A61P25/24; A61P25/30; A61P25/32; A61P25/34; A61P27/02; A61P39/02; A61P43/00; C07D401/12; C07D405/12; C07D409/12
Attorney, Agent or Firm:
Kyousei Tamura
Toshio Ueda
Nagatoshi Shinagawa
Toshio Ueda
Nagatoshi Shinagawa