Title:
プロリルヒドロキシラーゼインヒビタとしての４−アミノキナゾリン−２−イル−１−ピラゾール−４−カルボン酸化合物
Document Type and Number:
Japanese Patent JP5755741
Kind Code:
B2
Abstract:
which are useful as prolyl hydroxylase inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by prolyl hydroxylase activity. Thus, the compounds may be administered to treat, e.g., anemia, vascular disorders, metabolic disorders, and wound healing.
Inventors:
Rabinowitz, Michael, H.
Rosen, Mark, Dee.
Tarantino, Kyle, Tea.
Venkatesan, Hari Haran
Rosen, Mark, Dee.
Tarantino, Kyle, Tea.
Venkatesan, Hari Haran
Application Number:
JP2013524250A
Publication Date:
July 29, 2015
Filing Date:
August 12, 2011
Export Citation:
Assignee:
Janssen Pharmaceuticals N.B.
International Classes:
C07D401/14; A61K31/517; A61K31/5377; A61K31/541; A61K31/55; A61K31/551; A61P1/04; A61P3/04; A61P3/10; A61P7/06; A61P9/00; A61P9/10; A61P17/02; A61P19/00; A61P31/00; A61P43/00; C07D403/04; C07D405/14
Domestic Patent References:
| JP2010507606A | ||||
| JP2009541486A |
Foreign References:
| US20100204226 | ||||
| WO2009117269A1 |
Other References:
Bioorganic & Medicinal Chemistry Letters,2006年,Vol.16 No.21,p.5687-5690
Bioorganic & Medicinal Chemistry Letters,2006年,Vol.16 No.21,p.5616-5620
Bioorganic & Medicinal Chemistry Letters,2006年,Vol.16 No.21,p.5616-5620
Attorney, Agent or Firm:
Hiroshi Kobayashi
Junko Kobayashi
Norio Omori
Yasuhito Suzuki
Junko Kobayashi
Norio Omori
Yasuhito Suzuki