Title:
4-{ [(pyridine 3- Il - methyl) Aminocarbonyl] Amino} Ben Zen - Sour Hong derivative as NAMPT inhibitor for the medical treatment of diseases, such as cancer
Document Type and Number:
Japanese Patent JP6038792
Kind Code:
B2
Abstract:
The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An embodiment of the invention is the provision of a compound of Formula IIIA.
Inventors:
Bear, Kenneth W.
Bow Meister, Tim Earl.
Buck Melter, Alexandre J.
Clodfelter, Karl H.
Han, Pinson
Lynn, Chen
Reynolds, Dominique J.
Smith, Chase Sea.
Wang, Chong Kuo
Chung, Xiao Chang
Yun, Paw-Wye
Bow Meister, Tim Earl.
Buck Melter, Alexandre J.
Clodfelter, Karl H.
Han, Pinson
Lynn, Chen
Reynolds, Dominique J.
Smith, Chase Sea.
Wang, Chong Kuo
Chung, Xiao Chang
Yun, Paw-Wye
Application Number:
JP2013527339A
Publication Date:
December 07, 2016
Filing Date:
September 02, 2011
Export Citation:
Assignee:
Former Tm, LLC.
Genentech, Incorporated
Genentech, Incorporated
International Classes:
C07D213/40; A61K31/44; A61K31/4406; A61K31/4427; A61K31/443; A61K31/4433; A61K31/4436; A61K31/4439; A61K31/444; A61K31/4545; A61K31/4709; A61K31/4725; A61K31/473; A61K31/496; A61K31/497; A61K31/506; A61K31/5377; A61K31/5386; A61K31/541; A61K31/55; A61K31/551; A61P1/04; A61P3/00; A61P3/10; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P17/00; A61P17/06; A61P19/02; A61P19/10; A61P25/00; A61P25/28; A61P29/00; A61P31/12; A61P31/18; A61P31/22; A61P35/00; A61P35/02; A61P37/02; A61P37/08; C07D213/64; C07D213/89; C07D401/04; C07D401/12; C07D401/14; C07D405/12; C07D409/12; C07D411/12; C07D413/12; C07D451/02; C07D471/04; C07D471/10; C07D491/107; C07D498/08
Foreign References:
| WO2011109441A1 |
Attorney, Agent or Firm:
Sonoda Yoshitaka
Kobayashi Yoshinori
Kobayashi Yoshinori