Title:
ヒドラジノ1H-イミダゾキノリン-4-アミン及びこれから調製された複合体
Document Type and Number:
Japanese Patent JP6430574
Kind Code:
B2
Abstract:
1H-Imidazo[4,5-c]quinolin-4-amines substituted at the 1-position with a substituent bearing a hydrazinobenzamide or hydrazinonicotinamide, a salt thereof, or a protected hydrazinobenzamide or hydrazinonicotinamide and conjugates made from such compounds are disclosed. Pharmaceutical compositions containing the compound or the conjugate, methods of making a conjugate, and methods of use of the compounds or conjugates as immunomodulators for inducing cytokine biosynthesis in an animal and for vaccinating an animal are also disclosed.
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Inventors:
Paul Dee Wightman
Application Number:
JP2017078814A
Publication Date:
November 28, 2018
Filing Date:
April 12, 2017
Export Citation:
Assignee:
3M INNOVATIVE PROPERTIES COMPANY
International Classes:
A61K39/00; A61K39/002; A61K39/02; A61K39/04; A61K39/05; A61K39/07; A61K39/08; A61K39/09; A61K39/095; A61K39/102; A61K39/112; A61K39/12; A61K39/145; A61K39/15; A61K39/155; A61K39/165; A61K39/20; A61K39/205; A61K39/21; A61K39/215; A61K39/235; A61K39/245; A61K39/25; A61K39/29; A61P31/04; A61P31/06; A61P31/10; A61P31/12; A61P31/14; A61P31/16; A61P31/18; A61P31/20; A61P31/22; A61P35/00
Domestic Patent References:
JP2006507265A | ||||
JP2005539067A | ||||
JP2010518082A |
Foreign References:
WO2007097934A1 | ||||
US20090035323 | ||||
US20060142202 | ||||
US20060045885 | ||||
US20050175630 |
Other References:
G. Iyer et al,Aromatic aldehyde and Hydrazine activated peptide coated quantum dots for easy bioconjugation and li,Bioconjugate Chemistry,2011年,22,1006-1011
Attorney, Agent or Firm:
Taro Akazawa
Wakako Nomura
Tsukuda Seigen
Ryohei Yoshino
Wakako Nomura
Tsukuda Seigen
Ryohei Yoshino