Title:
(5, 6)-CIS-1, 3-OXATHIANE DERIVATIVE, ITS PRODUCTION AND PHARMACEUTICAL COMPOSITION CONTAINING SAID COMPOUND
Document Type and Number:
Japanese Patent JPS6212775
Kind Code:
A
Abstract:
The invention concerns novel [5,6]-cis-1,3-oxathiane derivatives of formula I in which R1 and R2 are variously defined as hydrogen, alkyl, trifluoromethyl or phenyl (as set out in the specification), n is 1 or 2, m is 2, 3 or 4, Y is vinylene and Z is carboxy, 1(H)-tetrazol-5-yl or a group of the formula -CO.NH.SO2R3 in which R3 is alkyl, phenyl or benzyl, and pharmaceutically acceptable salts thereof, for use in conjunction with their pharmaceutical compositions in treating certain pulmonary and/or vascular disorders. The invention also describes various processes and intermediates for the manufacture of the novel compounds.
Inventors:
BUIKUTAA JIYURIO MATATSUSA
MAIKERU JIEEMUZU SUMISAAZU
MAIKERU JIEEMUZU SUMISAAZU
Application Number:
JP10656486A
Publication Date:
January 21, 1987
Filing Date:
May 09, 1986
Export Citation:
Assignee:
ICI PLC
International Classes:
A61K31/39; A61K31/41; A61P7/02; A61P9/08; A61P9/10; C07D327/06; C07D411/06; (IPC1-7): A61K31/39; C07D327/06
Attorney, Agent or Firm:
Toshio Yano